Interanimal transfer and chemical events underlying the kindling effect

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The protective effect of auraptene against oxidative stress and pentylenetetrazol-induced chemical kindling in mice

It is believed that some pitfalls in the treatment of epilepsy including serious side effects of medications and drug resistance may be resolved by natural compounds. Auraptene is a natural coumarin that is found in many plants, particularly citrus peel. We hypothesized that auraptene might have anticonvulsant properties. Kindling was induced by repeated intraperitoneal (IP) injections of penty...

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The protective effect of auraptene against oxidative stress and pentylenetetrazol-induced chemical kindling in mice

It is believed that some pitfalls in the treatment of epilepsy including serious side effects of medications and drug resistance may be resolved by natural compounds. Auraptene is a natural coumarin that is found in many plants, particularly citrus peel. We hypothesized that auraptene might have anticonvulsant properties. Kindling was induced by repeated intraperitoneal (IP) injections of penty...

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Inhibitory effects of succinic acid on chemical kindling and amygdala electrical kindling in rats.

AIM To investigate the effects and mechanism of succinic acid on pentylenetetrazol (PTZ) chemical kindling and amygdala electrical kindling in rats. METHODS PTZ chemical kindling and amygdala electrical kindling models were established in rats. The effects of succinic acid on the behavior and afterdischarge of kindled rats were observed. The mice were pretreated with succinic acid, 30 min lat...

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Protective Effect of Quinine on Chemical Kindling and Passive Avoidance Test in Rats

BACKGROUND In humans, convulsive diseases such as temporal lobe epilepsy are usually accompanied by learning and memory impairments. In recent years, the role of gap junction channels as an important target of antiepileptic drugs has been studied and discussed. Quinine, as a gap junction blocker of connexin 36, can abolish ictal epileptiform activity in brain slices. OBJECTIVES The role of qu...

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ژورنال

عنوان ژورنال: Bulletin of the Psychonomic Society

سال: 1973

ISSN: 0090-5054

DOI: 10.3758/bf03334357